Browsing by Subject "oxidative stress"
Now showing items 1-18 of 18
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(2021-10-12)Copper is an essential trace element that can produce reactive oxygen species (ROS). Excess ROS promote oxidative stress, which can lead to hepatic injury. Copper-associated hepatopathy is well-studied in humans and dogs. ...
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(2012-07-16)Nanoparticles, while included in a growing number of consumer products, may pose risks to human health due to heavy metal leaching and/or the production of reactive oxygen species following exposures. Subcellular mechanisms ...
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(Texas A&M University, 2004-09-30)Chronic oxidative injury by allylamine induces proliferative vascular smooth muscle cell (vSMC) phenotypes in the rat aorta similar to those seen in rodent and human atherosclerotic lesions. In this study, we evaluate the ...
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(Texas A&M University, 2004-09-30)NF-κB activity is critical in the regulation of atherosclerotic vascular smooth muscle cell (vSMC) phenotypes induced following oxidative injury by allylamine. The present studies were designed to detail dysregulation of ...
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(2017-04-28)This study was designed to observe the effects of an antioxidant gel on oxidative stress levels and salivary flow rates in xerostomic patients. In this prospective, nested, double blind, crossover, randomized clinical ...
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(Texas A&M University, 2006-08-16)Colon cancer is one of the most commonly diagnosed cancers in the US, yet small intestine cancer is a rare event. While there are many similarities between these two tissues, inherent differences such as redox status, may ...
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(2013-04-19)Astronauts in space flight missions are exposed to increased iron (Fe) stores and galactic cosmic radiation, both of which independently induce oxidative stress. Oxidative stress can result in protein, lipid, and DNA ...
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(2017-05-25)Recent progress has been made in understanding the physiological responses to conditions prevalent in the space flight environment, including radiation source, duration of radiation exposure, weightlessness, and diet. The ...
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(2017-12-09)In recent years, there has been increased interest into better understanding how environmental In recent years, there has been increased interest into better understanding how environmental exposures influence the long-term ...
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(2009-05-15)Based on the ‘free radical theory of aging,’ I hypothesized that hypoxia caused by the mammalian dive response induces free radical production which could modulate or accelerate cellular aging. On the other hand, to prevent ...
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(Texas A&M University, 2007-04-25)Gene expression was examined in vascular smooth muscle cells to study the complex interaction between oxidative injury and the pathogenesis of vascular disease. Extensive vascular remodeling coupled to increased production ...
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(2016-08-03)Cell-penetrating peptides (CPPs) enter cells primarily through escaping from endosomal compartments or directly translocating across the plasma membrane. Due to their capability of permeating into the cytosolic space of ...
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(2017-12-13)We have previously shown that partial inhibition of mitochondrial complex I activity with a small molecule tricycle pyrone compound (code name CP2) averted the development of cognitive and behavior phenotypes in multiple ...
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(1998)The hazards of Pb exposure has been a topic of concern for many years. This research was developed to investigate the possibility of Pb induced oxidative stress. The research objectives were to observe Pb induced lipid ...
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(2014-05-06)Cadmium (Cd) is a toxic heavy metal with no known physiological function in higher order animals. Previous studies in primary cultures of neonatal rat choroid plexus (CP) epithelial cells indicated Cd induced oxidative ...
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(2012-07-16)The overall goal of this research was to investigate oxidative stress related changes to the proteomes of 3T3-L1 adipocytes and an inducible CYP2E1 expressing HepG2 cells. Enhanced oxidative stress in hypertrophic adipocytes ...
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(2020-03-27)The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long noncoding RNA and its overexpression is associated with poor prognosis of many types of cancers and its silencing has been reported to reverse ...
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(2015-04-29)Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology. Typical management of OLP involves topical corticosteroids. Recent literature shows an association between high levels of various oxidative ...